Cloned (Comment) | Organism |
---|---|
activity of PBP1a or PBP1b can be measured in membranes by cloning the PBP into an Escherichia coli ponB::Spcr strain | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Moenomycin | coupled transglycosylasetranspeptidase | Escherichia coli | |
nisin | - |
Escherichia coli | |
penicillin | coupled transglycosylasetranspeptidase | Escherichia coli | |
tunicamycin | - |
Escherichia coli |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Escherichia coli | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol | PBP1a and PBP1b have both transglycosylase and transpeptidase activity | Escherichia coli | [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PBP1a | the enzyme has both transglycosylase and transpeptidase activity | Escherichia coli |
PBP1b | the enzyme has both transglycosylase and transpeptidase activity | Escherichia coli |
penicillin-binding protein 1a | the enzyme has both transglycosylase and transpeptidase activity | Escherichia coli |
penicillin-binding protein 1B | the enzyme has both transglycosylase and transpeptidase activity | Escherichia coli |