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Literature summary for 2.4.1.122 extracted from

  • Gerken, T.A.
    Kinetic modeling confirms the biosynthesis of mucin core 1 (beta-Gal(1-3) alpha-GalNAc-O-Ser/Thr) O-glycan structures are modulated by neighboring glycosylation effects (2004), Biochemistry, 43, 4137-4142.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information kinetic modeling, numerical simulation of in vivo Core 1 glycosylation pattern Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-galactose + glycoprotein N-acetyl-D-galactosamine Sus scrofa the enzyme can O-glycosylate the mucin-like domains of glycoproteins in a site-specific manner dependent on the sort of glycosylation/presence of glycan C-terminal from site of action, a position specific glycosylation pattern results, regulation, overview UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
?
UDP-galactose + salivary gland mucin 81 N-acetyl-D-galactosamine Sus scrofa glycosylation pattern of the mucin, overview UDP + salivary gland mucin 81 D-galactosyl-1,3-N-acetyl-D-galactosamine
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
salivary gland
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-galactose + glycoprotein N-acetyl-D-galactosamine
-
Sus scrofa UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
?
UDP-galactose + glycoprotein N-acetyl-D-galactosamine the enzyme can O-glycosylate the mucin-like domains of glycoproteins in a site-specific manner dependent on the sort of glycosylation/presence of glycan C-terminal from site of action, a position specific glycosylation pattern results, regulation, overview Sus scrofa UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
?
UDP-galactose + salivary gland mucin 81 N-acetyl-D-galactosamine
-
Sus scrofa UDP + salivary gland mucin 81 D-galactosyl-1,3-N-acetyl-D-galactosamine
-
?
UDP-galactose + salivary gland mucin 81 N-acetyl-D-galactosamine glycosylation pattern of the mucin, overview Sus scrofa UDP + salivary gland mucin 81 D-galactosyl-1,3-N-acetyl-D-galactosamine
-
?

Synonyms

Synonyms Comment Organism
core 1 transferase
-
Sus scrofa
UDP-galactose:glycoprotein-alpha-GalNAc beta3-galactosyltransferase
-
Sus scrofa