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Literature summary for 2.4.1.11 extracted from

  • Ortmeyer, H.K.; Adall, Y.; Marciani, K.R.; Katsiaras, A.; Ryan, A.S.; Bodkin, N.L.; Hansen, B.C.
    Skeletal muscle glycogen synthase subcellular localization: effects of insulin and PPAR-alpha agonist (K-111) administration in rhesus monkeys (2005), Am. J. Physiol. Regul. Integr. Comp. Physiol., 288, R1509-R1517.
    View publication on PubMed
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Localization

Localization Comment Organism GeneOntology No. Textmining
additional information neither glycogen synthase activity nor glycogen synthase protein are present in the cytosolic fraction of subfractionated skeletal muscle obtained after an overnight fast or after 90 min of insulin infusion during a hyperinsulinemic euglycemic clamp in healthy or in insulin-resistant monkeys. Glycogen synthase activity, glycogen synthase protein, and glycogen are present in all other fractions. In vivo insulin regulation of skeletal muscle glycogen synthase activity does not involve changes in the subcellular localization of glycogen synthase. One mechanism by which peroxisome proliferator-activated receptor-alpha agonist treatment improves whole body insulin sensitivity is by increasing skeletal muscle GS total activity Macaca mulatta
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Macaca mulatta one mechanism by which peroxisome proliferator-activated receptor-alpha agonist treatment improves whole body insulin sensitivity is by increasing skeletal muscle GS total activity ?
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Organism

Organism UniProt Comment Textmining
Macaca mulatta Q8MJ26
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Source Tissue

Source Tissue Comment Organism Textmining
adipose tissue
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 Macaca mulatta
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skeletal muscle
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 Macaca mulatta
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information one mechanism by which peroxisome proliferator-activated receptor-alpha agonist treatment improves whole body insulin sensitivity is by increasing skeletal muscle GS total activity Macaca mulatta ?
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