Literature summary for 2.4.1.11 extracted from

Ruzzin, J.; Jensen, J.
Contraction activates glucose uptake and glycogen synthase normally in muscles from dexamethasone-treated rats (2005), Am. J. Physiol. Endocrinol. Metab., 289, E241-E250.

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	in the absence of insulin, glycogen synthase Ser645, Ser649, Ser653, and Ser657 phosphorylation is similar in soleus muscles from control and dexamethasone-treated rats. In epitrochlearis, glycogen synthase phosphorylation is slightly elevated in muscles from dexamethasone-treated rats. Contraction decreases glycogen synthase Ser645, Ser649, Ser653, and Ser657 phosphorylation in soleus to a similar low level in muscles from control and dexamethasone-treated rats. In epitrochlearis muscles, contraction also decreases glycogen synthase phosphorylation to a low level in muscles from control and dexamethasone-treated rats. In soleus and epitrochlearis muscles, the combination of contraction and insulin does not decrease glycogen synthase phosphorylation more than contraction alone	Rattus norvegicus

Source Tissue

Source Tissue	Comment	Organism	Textmining
muscle	contraction activates glycogen synthase in muscles from dexamethasone-treated rats	Rattus norvegicus	-

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Release 2023.1 (January 2023)