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Literature summary for 2.4.1.11 extracted from

  • Zea, C.J.; MacDonell, S.W.; Pohl, N.L.
    Discovery of the archaeal chemical link between glycogen (starch) synthase families using a new mass spectrometry assay (2003), J. Am. Chem. Soc., 125, 13666-13667.
    View publication on PubMed
Search for more literature for 2.4.1.11

Inhibitors

Inhibitors Comment Organism Structure
ADP-glucose competitive with UDPglucose Pyrococcus furiosus
UDP-glucose competitive with ADP-glucose Pyrococcus furiosus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1
-
 UDP-glucose
-
 Pyrococcus furiosus
4.3
-
 ADP-glucose
-
 Pyrococcus furiosus

Organism

Organism UniProt Comment Textmining
Pyrococcus furiosus
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 assay based on ESI-mass spectrometry enables detection of submicromolar quantities of substrate, thus requiring even lower concentrations of protein and is amenable to high throughput screening methods Pyrococcus furiosus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP-glucose + glycogen
-
 Pyrococcus furiosus ? + ADP
-
 ?
UDP-glucose + glycogen
-
 Pyrococcus furiosus glycogen + UDP
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
80
-
-
 Pyrococcus furiosus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
-
 Pyrococcus furiosus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
18
-
 UDP-glucose
-
 Pyrococcus furiosus
22
-
 ADP-glucose
-
 Pyrococcus furiosus