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Literature summary for 2.4.1.11 extracted from
- Purification and properties of glycogen synthase I from skeletal muscle: two kinetic forms (1973), Biochim. Biophys. Acta, 293, 73-83.
General Stability
| General Stability | Organism |
|---|---|
| sulfate stabilizes | Oryctolagus cuniculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| NaCl | above 100 mM | Oryctolagus cuniculus |  |
| UTP | - |
Oryctolagus cuniculus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.05 | - |
UDP-glucose | with Na2SO4, form I | Oryctolagus cuniculus | |
| 0.11 | - |
UDP-glucose | without Na2SO4, form I | Oryctolagus cuniculus | |
| 0.27 | - |
UDP-glucose | with Na2SO4, form II | Oryctolagus cuniculus | |
| 0.72 | - |
UDP-glucose | without Na2SO4, form II | Oryctolagus cuniculus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-glucose + glycogen | Oryctolagus cuniculus | - |
glycogen + UDP | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| muscle | - |
Oryctolagus cuniculus | - |
| skeletal muscle | - |
Oryctolagus cuniculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 5.2 | - |
- |
Oryctolagus cuniculus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -60°C, stable for 2 months | Oryctolagus cuniculus |
| 4°C, stable for several days | Oryctolagus cuniculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-glucose + glycogen | - |
Oryctolagus cuniculus | glycogen + UDP | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
stable up to 60 min | Oryctolagus cuniculus |
| 42 | - |
inactivation after 30 min, sulfate protects | Oryctolagus cuniculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
synthase I | Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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