Application | Comment | Organism |
---|---|---|
analysis | assays for gamma-glutamyl transferase (GGT1) activity in blood are widely used in a clinical setting to measure tissue damage | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
vacuole | GGT1 is an extracellular enzyme that is anchored to the plasma membrane of cells | Homo sapiens | 5773 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | GGT1 hydrolyzes and transfers gamma-glutamyl moieties from glutathione and other gamma-glutamyl compounds to acceptors. It has a critical function in the metabolism of glutathione and in the conversion of the leukotriene LTC4 to LTD4 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P19440 | precursor | - |
Homo sapiens | P36269 | precursor | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Homo sapiens | - |
bladder | - |
Homo sapiens | - |
blood | - |
Homo sapiens | - |
lymph | - |
Homo sapiens | - |
mammary gland | - |
Homo sapiens | - |
additional information | activity of GGT1 is increased in liver disease, oxidative stress and metabolic syndrome | Homo sapiens | - |
prostate | - |
Homo sapiens | - |
spleen | - |
Homo sapiens | - |
thymus | - |
Homo sapiens | - |
vascular tissue | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | GGT1 hydrolyzes and transfers gamma-glutamyl moieties from glutathione and other gamma-glutamyl compounds to acceptors. It has a critical function in the metabolism of glutathione and in the conversion of the leukotriene LTC4 to LTD4 | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GGT1 | - |
Homo sapiens |
GGT5 | - |
Homo sapiens |
GGTLA1 | formerly | Homo sapiens |