Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.2.2 extracted from

  • Indirani, N.; Hill, P.G.
    Partial purification and some properties of gamma-glutamyl transpeptidase from human bile (1977), Biochim. Biophys. Acta, 483, 57-62.
    View publication on PubMed
Search for more literature for 2.3.2.2

Activating Compound

Activating Compound Comment Organism Structure
additional information effect of amino acids on activity Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information inhibition by diverse amino acids, overview Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.5
-
 L-Glu-4-nitroanilide bile enzyme Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ no effect Homo sapiens
K+ no effect Homo sapiens
Li+ no effect Homo sapiens
Mg2+ no effect Homo sapiens
additional information no activation by Zn2+ and Mn2+ Homo sapiens
Na+ no effect Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial from bile Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
bile
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
81
-
 purified enzyme Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(5-L-glutamyl)-peptide + acceptor + H+ acceptor specificity, overview Homo sapiens peptide + 5-L-glutamyl amino acid
-
 ?
5-L-glutamyl-4-nitroanilide + glycyl-L-proline
-
 Homo sapiens 4-nitroaniline + 5-L-glutamyl-glycyl-L-proline
-
 ?
5-L-glutamyl-4-nitroanilide + glycylglycine
-
 Homo sapiens 4-nitroaniline + 5-L-glutamylglycylglycine
-
 ?
5-L-glutamyl-4-nitroanilide + L-glutamine
-
 Homo sapiens 4-nitroaniline + 5-L-glutamyl-L-glutamine
-
 ?
5-L-glutamyl-4-nitroanilide + L-leucyl-L-alanine
-
 Homo sapiens 4-nitroaniline + 5-L-glutamyl-L-leucyl-L-alanine
-
 ?
L-Glu-4-nitroanilide + glutathione
-
 Homo sapiens 4-nitroaniline + 5-L-glutamyl-glutathione
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.1
-
-
 Homo sapiens

pH Range

pH Minimum pH Maximum Comment Organism
7 9
-
 Homo sapiens