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Literature summary for 2.3.2.13 extracted from

  • Le, B.V.; Nguyen, J.B.; Logarajah, S.; Wang, B.; Marcus, J.; Williams, H.P.; Catteruccia, F.; Baxter, R.H.
    Characterization of Anopheles gambiae transglutaminase 3 (AgTG3) and its native substrate plugin (2013), J. Biol. Chem., 288, 4844-4853.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Rosetta cells Anopheles gambiae

Inhibitors

Inhibitors Comment Organism Structure
iodoacetamide complete inhibition at 50 mM Anopheles gambiae

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Anopheles gambiae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
90000
-
2 * 90000, SDS-PAGE Anopheles gambiae
160000
-
gel filtration Anopheles gambiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
plugin glutamine + alkylamine Anopheles gambiae preferred substrate plugin N5-alkylglutamine + NH3
-
?

Organism

Organism UniProt Comment Textmining
Anopheles gambiae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
HisTrap column chromatography, and Superdex 200 gel filtration Anopheles gambiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
plugin glutamine + alkylamine preferred substrate Anopheles gambiae plugin N5-alkylglutamine + NH3
-
?
TVQQEL + alkylamine
-
Anopheles gambiae ?
-
?

Subunits

Subunits Comment Organism
homodimer 2 * 90000, SDS-PAGE Anopheles gambiae

Synonyms

Synonyms Comment Organism
TG3
-
Anopheles gambiae
transglutaminase 3
-
Anopheles gambiae