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Literature summary for 2.3.2.13 extracted from

  • Wang, Y.; Ande, S.R.; Mishra, S.
    Phosphorylation of transglutaminase 2 (TG2) at serine-216 plays a role in TG2 mediated activation of nuclear factor-kappa B and in the downregulation of PTEN (2012), BMC Cancer, 12, 277.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.2.13

Protein Variants

Protein Variants Comment Organism
S216A the mutant lacks the S216 phosphorylation site Mus musculus
S216A the mutant lacks the S216 phosphorylation site Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein phosphorylation of transglutaminase 2 (TG2) at serine-216 plays a role in TG2 mediated activation of nuclear factor-kappa B and in the downregulation of phosphatase and tensin homologue deleted on chromosome 10 Mus musculus
phosphoprotein phosphorylation of transglutaminase 2 (TG2) at serine-216 plays a role in TG2 mediated activation of nuclear factor-kappa B and in the downregulation of phosphatase and tensin homologue deleted on chromosome 10 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
MCF-7 cell
-
 Homo sapiens
-
MEF cell
-
 Mus musculus
-
T-47D cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
TG2
-
 Mus musculus
TG2
-
 Homo sapiens
transglutaminase 2
-
 Mus musculus
transglutaminase 2
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function phosphorylation of transglutaminase 2 at Ser216 plays a role in transglutaminase 2-mediated activation of nuclear factor-kappaB, Akt and in the downregulation of phosphatase and tensin homologue deleted on chromosome 10 Mus musculus
physiological function phosphorylation of transglutaminase 2 at Ser216 plays a role in transglutaminase 2-mediated activation of nuclear factor-kappaB, Akt and in the downregulation of phosphatase and tensin homologue deleted on chromosome 10 Homo sapiens