Literature summary for 2.3.2.13 extracted from

Zeugolis, D.I.; Panengad, P.P.; Yew, E.S.; Sheppard, C.; Phan, T.T.; Raghunath, M.
An in situ and in vitro investigation for the transglutaminase potential in tissue engineering (2010), J. Biomed. Mater. Res. A, 92, 1310-1320.

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Inhibitors

Inhibitors	Comment	Organism	Structure
BOC-DON-QIV-OMe	0.1 mM and 1 mM for normal skin and keloid scar, respectively	Homo sapiens
cystamine dihydrochloride	1 mM and 10 mM for normal skin and keloid scar, respectively	Homo sapiens
iodoacetamide	0.1 mM and 1 mM for normal skin and keloid scar, respectively	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
colon	muscularis mucosae	Homo sapiens	-
dermis	TGase activity in the basement membrane region	Homo sapiens	-
duodenum	muscularis mucosae	Homo sapiens	-
muscularis externa	of the small bowel	Homo sapiens	-
muscularis mucosa	of duodenum and colon	Homo sapiens	-
skin	epidermal TGase activity is observed in stratum granulosum	Homo sapiens	-
stratum granulosum	-	Homo sapiens	-

General Information

General Information	Comment	Organism
physiological function	TGase 2 has a role as a biological glue to consolidate various micro-structural components of tissues and biomaterials	Homo sapiens

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Release 2023.1 (January 2023)