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Literature summary for 2.3.2.13 extracted from

  • Candi, E.; Oddi, S.; Terrinoni, A.; Paradisi, A.; Ranalli, M.; Finazzi-Agro, A.; Melino, G.
    Transglutaminase 5 cross-links loricrin, involucrin, and small proline-rich proteins in vitro (2001), J. Biol. Chem., 276, 35014-35023.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0037
-
involucrin recombinant transglutaminase 5 Homo sapiens
0.0044
-
loricrin recombinant transglutaminase 5 Homo sapiens
0.0077
-
small proline-rich protein 3 recombinant transglutaminase 5 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
84000
-
x * 84000, recombinant transglutaminase 5, immunoblot Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
keratinocyte transglutaminase 5 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
involucrin + N,N'-dimethyl-casein
-
Homo sapiens ?
-
?
loricrin + N,N'-dimethyl-casein
-
Homo sapiens ?
-
?
loricrin + N,N'-dimethylcasein
-
Homo sapiens ?
-
?
protein-bound gamma-glutamine + alkylamine substrates of recombinant full-length transglutaminase 5: loricrin, small proline rich proteins 1, 2 and 3, and involucrin Homo sapiens protein N5-alkylglutamine + NH3
-
?
putrescine + N,N'-dimethylcasein transglutaminase 5 Homo sapiens ?
-
?
small proline-rich protein 3 + N,N'-dimethyl-casein
-
Homo sapiens ?
-
?
small proline-rich protein 3 + N,N'-dimethylcasein
-
Homo sapiens ?
-
?
vimentin + 5-(biotinamido)pentylamine transglutaminase 5 Homo sapiens ?
-
?

Subunits

Subunits Comment Organism
? x * 84000, recombinant transglutaminase 5, immunoblot Homo sapiens
More autocatalytic crosslinking of transglutaminase 5, molecular mass approx. 200000 Da Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.00233
-
involucrin recombinant transglutaminase 5 Homo sapiens
0.0035
-
loricrin recombinant transglutaminase 5 Homo sapiens
0.00433
-
small proline-rich protein 3 recombinant transglutaminase 5 Homo sapiens