Inhibitors | Comment | Organism | Structure |
---|---|---|---|
GDP | inhibits hydrolysis of GTP | Cavia porcellus | |
GDP | inhibits hydrolysis of GTP | Homo sapiens | |
GTP-gamma-S | inhibition of GTP-hydrolysis | Cavia porcellus | |
GTP-gamma-S | inhibition of GTP-hydrolysis | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0044 | - |
GTP | GTPase activity | Cavia porcellus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | requirement | Cavia porcellus | |
Ca2+ | requirement | Homo sapiens | |
Ca2+ | activation of GTPase activity | Cavia porcellus | |
Mg2+ | - |
Homo sapiens | |
Mg2+ | stimulation of GTPase activity, 5 mM | Cavia porcellus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
80000 | - |
1 * 80000, SDS-PAGE | Cavia porcellus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
affinity chromatography on GTP-agarose | Cavia porcellus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Cavia porcellus | - |
erythrocyte | - |
Homo sapiens | - |
liver | - |
Cavia porcellus | - |
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | intrinsic GTPase activity | Cavia porcellus | GDP + phosphate | - |
? | |
protein-bound gamma-glutamine + alkylamine | acyl-transfer reaction | Cavia porcellus | protein N5-alkylglutamine + NH3 | - |
? | |
protein-bound gamma-glutamine + alkylamine | acyl-transfer reaction | Homo sapiens | protein N5-alkylglutamine + NH3 | - |
? | |
putrescine + casein | - |
Cavia porcellus | ? | - |
? | |
putrescine + casein | - |
Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Homo sapiens |
monomer | 1 * 80000, SDS-PAGE | Cavia porcellus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Cavia porcellus |
37 | - |
assay at | Homo sapiens |