Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + serotonin | vertebrata | - |
CoA + N-acetylserotonin | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
vertebrata | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
vertebrata | - |
eye | - |
vertebrata | - |
pineal gland | photoreceptor cells, enzyme activity is regulated by circadian system, the photoperiodic control is direct in fish and frogs and indirect in mammals. Structural and functional evolution of the melatonin-producing units in vertebrates, overview | vertebrata | - |
retina | - |
vertebrata | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + serotonin | - |
vertebrata | CoA + N-acetylserotonin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AANAT | - |
vertebrata |
More | evolution of AANAT subtypes in vertebrates, overview | vertebrata |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
additional information | - |
pineal AANAT responds to temperature in a species-specific manner | vertebrata |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme catalyzes the rate-limiting step in melatonin synthesis, melatonin biosynthesis pathway overview | vertebrata |
physiological function | the enzyme catalyzes the rate-limiting step in melatonin synthesis, melatonin is a hormone acting as a synchronizer for the circadian system, overview. Evolution of the pineal gland and the circadian system involving melatonin, overview | vertebrata |