Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.86 extracted from

  • Ziegenhorn, J.; Niedermeier, R.; Nussler, C.; Lynen, F.
    Study of the acetyltransferase component of fatty acid synthetase of yeast (1972), Eur. J. Biochem., 30, 285-300.
    View publication on PubMed
Search for more literature for 2.3.1.86

Inhibitors

Inhibitors Comment Organism Structure
iodoacetamide beta-ketoacyl synthetase; no inhibition of acetyl transferase activity Saccharomyces cerevisiae
N-ethylmaleimide no inhibition of acetyl transferase activity Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + malonyl-CoA + NADH + NADPH Saccharomyces cerevisiae multifunctional enzyme involved in yeast fat metabolism ?
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 baker's yeast
-

Purification (Commentary)

Purification (Comment) Organism
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+
-
 Saccharomyces cerevisiae palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O
-
 ?
acetyl-CoA + malonyl-CoA + NADH + NADPH multifunctional enzyme involved in yeast fat metabolism Saccharomyces cerevisiae ?
-
 ?

Cofactor

Cofactor Comment Organism Structure
NADPH requirement Saccharomyces cerevisiae