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Literature summary for 2.3.1.85 extracted from

  • Joshi, A.K.; Rangan, V.S.; Witkowski, A.; Smith, S.
    Engineering of an active animal fatty acid synthase dimer with only one competent subunit (2003), Chem. Biol., 10, 169-173.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information engineering of a enzyme containing one wild-type subunit and one subunit comprised by mutations in all seven functional domains. Mutant enzyme is active Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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-
-

Reaction

Reaction Comment Organism Reaction ID
acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O scheme of functional interactions between constituent domains. A single subunit, in context of a dimer, is able to catalyze the entire biosynthetic pathway Rattus norvegicus