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Literature summary for 2.3.1.50 extracted from

  • Garnepudi, V.R.; Zhao, C.; Beeler, T.; Dunn, T.
    Serine palmitoyltransferase (scs1/lcb2) mutants have elevated copy number of the L-A dsRNA virus (1997), Yeast, 13, 299-304.
    View publication on PubMed
Search for more literature for 2.3.1.50

Protein Variants

Protein Variants Comment Organism
additional information natural mutant strains: SCS1/LCB2 knock-out mutant, scs1-1 mutant shows reduced activity, scs1-2 mutant is temperature-sensitive, but shows normal enzyme activity Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome microsome isolation from mutant strains Saccharomyces cerevisiae
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
90000
-
 x * 90000, SDS-PAGE Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
palmitoyl-CoA + L-serine Saccharomyces cerevisiae
-
 CoA + 3-dehydro-D-sphinganine + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 gene LCB1/SCS1
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
palmitoyl-CoA + L-serine
-
 Saccharomyces cerevisiae CoA + 3-dehydro-D-sphinganine + CO2
-
 ?

Subunits

Subunits Comment Organism
? x * 90000, SDS-PAGE Saccharomyces cerevisiae

Synonyms

Synonyms Comment Organism
More the amount of enzyme activity in microsomes is inversely correlated with the amount of the major coat Gag protein of the L-A dsRNA virus particles Saccharomyces cerevisiae