Activating Compound | Comment | Organism | Structure |
---|---|---|---|
TNF-alpha | a significant induction of NF-kB p65-associated HAT activity by TNF-alpha is demonstrated, which is attenuated by the presence of montelukast in a concentration-dependent manner | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
montelukast | decreases HAT activity by attenuating the activating effect of TNF-alpha | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
U-937 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + histone H4 | - |
Homo sapiens | CoA + acetylhistone H4 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HAT | - |
Homo sapiens |
histone acetyltransferase | - |
Homo sapiens |