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Literature summary for 2.3.1.199 extracted from

  • Lee, S.; Jung, S.; Go, Y.; Kim, H.; Kim, J.; Cho, H.; Park, O.; Suh, M.
    Two Arabidopsis 3-ketoacyl CoA synthase genes, KCS20 and KCS2/DAISY, are functionally redundant in cuticular wax and root suberin biosynthesis, but differentially controlled by osmotic stress (2009), Plant J., 60, 462-475.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
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ecotype Columbia-0
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Source Tissue

Source Tissue Comment Organism Textmining
cauline leaf
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Arabidopsis thaliana
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epidermis isoform KCS20 and KCS2/DAISY transcripts are approximately 4 and 2fold higher in epidermal peels than in stem Arabidopsis thaliana
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flower highest expression of isoform KCS2/DAISY Arabidopsis thaliana
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leaf
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Arabidopsis thaliana
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root
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Arabidopsis thaliana
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seedling highest expression of isoform KCS20 Arabidopsis thaliana
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silique
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Arabidopsis thaliana
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stem
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Arabidopsis thaliana
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
very-long-chain acyl-CoA + malonyl-CoA
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Arabidopsis thaliana CoA + very-long-chain 3-oxoacyl-CoA + CO2
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Synonyms

Synonyms Comment Organism
3-ketoacyl CoA synthase
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Arabidopsis thaliana
KCS
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Arabidopsis thaliana
KCS2/DAISY isoform Arabidopsis thaliana
KCS20 isoform Arabidopsis thaliana

Expression

Organism Comment Expression
Arabidopsis thaliana isoform KCS20 mRNA expression is stimulated about 2fold by drought stress (air-drying for 6 h). Isoform KCS2/DAISY mRNA expression is stimulated about 4 fold at 200 mM mannitol, about 60fold at drought stress, about 3fold at 100 mM NaCl, and about 20fold at 0.1 mM abscisic acid up

General Information

General Information Comment Organism
malfunction complete loss of isoform KCS20 and KCS2 genes decreases the total wax content in stems and leaves by 20% and 15%, respectively. Kcs20 kcs2/daisy-1 double mutants exhibit significant reduction of C22 and C24 very-long-chain fatty acid derivatives but accumulation of C20 very-long-chain fatty acid derivatives in aliphatic suberin Arabidopsis thaliana
physiological function isoforms KCS20 and KCS2/DAISY are functionally redundant in the two-carbon elongation to C22 very-long-chain fatty acid that is required for cuticular wax and root suberin biosynthesis Arabidopsis thaliana