Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.199 extracted from

  • Katavic, V.; Barton, D.; Giblin, E.; Reed, D.; Kumar, A.; Taylor, D.
    Gaining insight into the role of serine 282 in B. napus FAE1 condensing enzyme (2004), FEBS Lett., 562, 118-124.
    View publication on PubMed
Search for more literature for 2.3.1.199

Cloned(Commentary)

Cloned (Comment) Organism
mutant enzymes are expressed in Saccharomyces cerevisiae Brassica napus

Protein Variants

Protein Variants Comment Organism
S282A the mutant shows reduced activity with 20:1DELTA11 and erucic acid-CoA as substrates compared to the wild type enzyme Brassica napus
S282C the mutant shows increased activity with 20:1DELTA11 and erucic acid-CoA as substrates compared to the wild type enzyme Brassica napus
S282G the mutant shows wild type activity with 20:1DELTA11 and erucic acid-CoA as substrates Brassica napus
S282I the mutant is inactive Brassica napus
S282N the mutant is inactive Brassica napus
S282Q the mutant is inactive Brassica napus
S282T the mutant shows reduced activity with 20:1DELTA11 and erucic acid-CoA as substrates compared to the wild type enzyme Brassica napus
S282V the mutant is inactive Brassica napus
S282Y the mutant is inactive Brassica napus

Organism

Organism UniProt Comment Textmining
Brassica napus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(11Z)-eicosenoyl-CoA + malonyl-CoA
-
 Brassica napus ?
-
 ?
erucoyl-CoA + malonyl-CoA 22:1DELTA13 Brassica napus ?
-
 ?
very-long-chain acyl-CoA + malonyl-CoA
-
 Brassica napus CoA + very-long-chain 3-oxoacyl-CoA + CO2
-
 ?

Synonyms

Synonyms Comment Organism
3-ketoacyl-CoA synthase
-
 Brassica napus
FAE1
-
 Brassica napus
fatty acid elongase 1
-
 Brassica napus
seed-specific condensing enzyme
-
 Brassica napus