Inhibitors | Comment | Organism | Structure |
---|---|---|---|
guanidine hydrochloride | 50% inhibition at 0.3 M, complete inhibition at 0.7-1 M | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
82000 | - |
3 * 82000, gel filtration, trimeric form occurs in solutions with 4 M guanidine hydrochloride | Homo sapiens |
200000 | - |
at 1.8 - 2.8 M guanidine hydrochloride, complex dissociates at higher guanidine hydrochloride levels to a monomeric form with MW 82000 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dihydrolipoamide + acetyl-CoA | Homo sapiens | - |
S-acetyldihydrolipoamide + CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Renatured (Comment) | Organism |
---|---|
treatment with guanidine hydrochloride and its subsequent removal results in refolding | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dihydrolipoamide + acetyl-CoA | - |
Homo sapiens | S-acetyldihydrolipoamide + CoA | - |
? |
Subunits | Comment | Organism |
---|---|---|
trimer | 3 * 82000, gel filtration, trimeric form occurs in solutions with 4 M guanidine hydrochloride | Homo sapiens |