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Literature summary for 2.3.1.12 extracted from
- A new dihydrolipoamide transacetylase in Escherichia coli K12 (1973), Biochim. Biophys. Acta, 321, 143-148.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 4.2 | - |
dihydrolipoamide | - |
Escherichia coli |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 150000 | - |
no component of pyruvate dehydrogenase complex, sucrose density gradient centrifugation | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dihydrolipoamide + acetyl-CoA | Escherichia coli | - |
S-acetyldihydrolipoamide + CoA | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
K-12, wild-type and mutant strains | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
specific activity after growth on various carbon sources | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dihydrolipoamide + acetyl-CoA | - |
Escherichia coli | S-acetyldihydrolipoamide + CoA | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | multimer formation is probably lost by loss of a small segment during genetic rearrangement | Escherichia coli |
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Release 2023.1 (January 2023)
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