Literature summary for 2.2.1.6 extracted from

Sohn, H.; Lee, K.S.; Ko, Y.K.; Ryu, J.W.; Woo, J.C.; Koo, D.W.; Shin, S.J.; Ahn, S.J.; Shin, A.R.; Song, C.H.; Jo, E.K.; Park, J.K.; Kim, H.J.
In vitro and ex vivo activity of new derivatives of acetohydroxyacid synthase inhibitors against Mycobacterium tuberculosis and non-tuberculous mycobacteria (2008), Int. J. Antimicrob. Agents, 31, 567-571.

Inhibitors

Inhibitors	Comment	Organism
4-(cyclopropylcarbonyl)-N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-1H-pyrazole-5-sulfonamide	i.e. K13030	Mycobacterium tuberculosis
4-acetyl-N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-1H-pyrazole-5-sulfonamide	i.e. K13010	Mycobacterium tuberculosis
isoniazid	-	Mycobacterium avium
isoniazid	-	Mycobacterium kansasii
isoniazid	-	Mycobacterium tuberculosis
isoniazid	-	Mycobacteroides abscessus
K12147	-	Mycobacterium avium
K12147	-	Mycobacterium kansasii
K12147	-	Mycobacteroides abscessus
K13010	-	Mycobacterium avium
K13010	-	Mycobacterium kansasii
K13010	-	Mycobacteroides abscessus
K13030	-	Mycobacterium avium
K13030	-	Mycobacterium kansasii
K13030	-	Mycobacteroides abscessus
metsulfuron methyl	-	Mycobacterium avium
metsulfuron methyl	-	Mycobacterium kansasii
metsulfuron methyl	-	Mycobacterium tuberculosis
metsulfuron methyl	-	Mycobacteroides abscessus
additional information	screening of 100 sulfonylurea analogues for antimycobacterial activity, minimal inhibitory concentrations, overview	Mycobacterium avium
additional information	screening of 100 sulfonylurea analogues for antimycobacterial activity, minimal inhibitory concentrations, overview	Mycobacterium kansasii
additional information	screening of 100 sulfonylurea analogues for antimycobacterial activity, minimal inhibitory concentrations, overview	Mycobacterium tuberculosis
additional information	screening of 100 sulfonylurea analogues for antimycobacterial activity, minimal inhibitory concentrations, overview	Mycobacteroides abscessus
N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-2-(ethylsulfanyl)-6-(2-fluoro-1-hydroxyethyl)benzenesulfonamide	i.e. K12147	Mycobacterium tuberculosis
pyrazosulfuron ethyl	-	Mycobacterium avium
pyrazosulfuron ethyl	-	Mycobacterium kansasii
pyrazosulfuron ethyl	-	Mycobacterium tuberculosis
pyrazosulfuron ethyl	-	Mycobacteroides abscessus
rifampicin	-	Mycobacterium avium
rifampicin	-	Mycobacterium kansasii
rifampicin	-	Mycobacterium tuberculosis
rifampicin	-	Mycobacteroides abscessus
sulfometuron methyl	the enzyme inhibitor shows activity against Mycobacterium tuberculosis both in vitro and in vivo	Mycobacterium avium
sulfometuron methyl	the enzyme inhibitor shows activity against Mycobacterium tuberculosis both in vitro and in vivo	Mycobacterium kansasii
sulfometuron methyl	active against Mycobacterium tuberculosis both in vitro and in vivo	Mycobacterium tuberculosis
sulfometuron methyl	the enzyme inhibitor shows activity against Mycobacterium tuberculosis both in vitro and in vivo	Mycobacteroides abscessus

Organism

Organism	UniProt	Comment	Textmining
Mycobacterium avium	-	-	-
Mycobacterium kansasii	-	-	-
Mycobacterium tuberculosis	-	wild-type strain H37Rv, ATCC 27294	-
Mycobacteroides abscessus	-	-	-

Synonyms

Synonyms	Comment	Organism
acetohydroxyacid synthase	-	Mycobacterium avium
acetohydroxyacid synthase	-	Mycobacterium tuberculosis
acetohydroxyacid synthase	-	Mycobacterium kansasii
acetohydroxyacid synthase	-	Mycobacteroides abscessus
AHAS	-	Mycobacterium avium
AHAS	-	Mycobacterium tuberculosis
AHAS	-	Mycobacterium kansasii
AHAS	-	Mycobacteroides abscessus