Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ATP | allosteric activator, up to 35% increase in Vmax | Pyrococcus abyssi | |
additional information | kinetic analysis of properties of allosteric effectors alone and in combination with each other | Pyrococcus abyssi |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CTP | allosteric inhibitor | Pyrococcus abyssi | |
additional information | kinetic analysis of properties of allosteric effectors alone and in combination with each other | Pyrococcus abyssi | |
UTP | allosteric inhibitor | Pyrococcus abyssi |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.005 | - |
Carbamoyl phosphate | 37°C | Pyrococcus abyssi |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
17000 | - |
6 * 35000 + 6 * 17000, 2C3/3R2 holoenzyme, calculated | Pyrococcus abyssi |
35000 | - |
6 * 35000 + 6 * 17000, 2C3/3R2 holoenzyme, calculated | Pyrococcus abyssi |
301000 | - |
gel filtration | Pyrococcus abyssi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pyrococcus abyssi | - |
recombinant protein | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate | cooperative mechanism of substrate binding | Pyrococcus abyssi |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
carbamoyl phosphate + L-aspartate | - |
Pyrococcus abyssi | phosphate + N-carbamoyl-L-aspartate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dodecamer | 6 * 35000 + 6 * 17000, 2C3/3R2 holoenzyme, calculated | Pyrococcus abyssi |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
90 | - |
half-life 260 min | Pyrococcus abyssi |
94 | - |
half-life 190 min | Pyrococcus abyssi |
98 | - |
half-life 100 min | Pyrococcus abyssi |