Literature summary for 2.1.1.77 extracted from

Waegner, A.M.; Cloos, P.; Bergholdt, R.; Eising, S.; Brorsson, C.; Stalhut, M.; Christgau, S.; Nerup, J.; Pociot, F.
Posttranslational protein modifications in type 1 diabetes - Genetic studies with PCMT1, the repair enzyme protein isoaspartate methyltransferase (PIMT) encoding gene (2008), Rev. Diabet. Stud., 5, 225-231.

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Application

Application	Comment	Organism
medicine	PCMT1 is associated with the type 1 diabetes in groups defined by other risk genes (SUMO4 and HLA)	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + protein L-isoaspartate	-	Homo sapiens	S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester	-	?

Synonyms

Synonyms	Comment	Organism
PCMT1	-	Homo sapiens
PIMT	-	Homo sapiens
protein L-isoaspartate (D-aspartate) O-methyltransferase	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
S-adenosyl-L-methionine	-	Homo sapiens

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Release 2023.1 (January 2023)