Literature summary for 2.1.1.77 extracted from

Gingras, D.; Menard, P.; Beliveau, R.
Protein carboxyl methylation in kidney brush-border membranes (1991), Biochim. Biophys. Acta, 1066, 261-267.

Search for more literature for 2.1.1.77

Inhibitors

Inhibitors	Comment	Organism	Structure
S-adenosylhomocysteine	-	Rattus norvegicus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.004	-	S-adenosyl-L-methionine	brush-border membrane isozyme	Rattus norvegicus
0.03	-	S-adenosyl-L-methionine	cytosolic isozyme	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
brush border	-	Rattus norvegicus	5903	-
cytosol	-	Rattus norvegicus	5829	-
membrane	-	Rattus norvegicus	16020	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
21000	-	brush-border membrane isozyme, SDS-PAGE	Rattus norvegicus
23000	-	cytosolic isozyme, SDS-PAGE	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
S-adenosyl-L-methionine + protein L-isoaspartate	Rattus norvegicus	post-translational covalent modification	S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester	-	r
S-adenosyl-L-methionine + protein L-isoaspartate	Rattus norvegicus Sprague-Dawley	post-translational covalent modification	S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester	-	r

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	Sprague-Dawley	-
Rattus norvegicus Sprague-Dawley	-	Sprague-Dawley	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
kidney	-	Rattus norvegicus	-
renal cortex	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + gelatin I	-	Rattus norvegicus	S-adenosyl-L-homocysteine + ?	-	?
S-adenosyl-L-methionine + gelatin I	-	Rattus norvegicus Sprague-Dawley	S-adenosyl-L-homocysteine + ?	-	?
S-adenosyl-L-methionine + ovalbumin	-	Rattus norvegicus	S-adenosyl-L-homocysteine + ?	-	?
S-adenosyl-L-methionine + ovalbumin	-	Rattus norvegicus Sprague-Dawley	S-adenosyl-L-homocysteine + ?	-	?
S-adenosyl-L-methionine + protein L-isoaspartate	-	Rattus norvegicus	S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester	-	r
S-adenosyl-L-methionine + protein L-isoaspartate	post-translational covalent modification	Rattus norvegicus	S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester	-	r
S-adenosyl-L-methionine + protein L-isoaspartate	-	Rattus norvegicus Sprague-Dawley	S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester	-	r
S-adenosyl-L-methionine + protein L-isoaspartate	post-translational covalent modification	Rattus norvegicus Sprague-Dawley	S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester	-	r

Synonyms

Synonyms	Comment	Organism
PCMT	-	Rattus norvegicus

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.5	-	-	Rattus norvegicus

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Release 2023.1 (January 2023)