Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli TRG8 | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C145A | inactive mutant protein | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
BrCH2OAc | reacts with the enzyme at its cysteine acceptor site, abolishing its DNA repair activity, the formation of AGT-Cys145S-CH2Br by BrCH2OAc | Homo sapiens | |
CH2Br2 | reacts with the enzyme at its cysteine acceptor site, abolishing its DNA repair activity | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA containing 4-O-methylthymine + [protein-L-cysteine | Homo sapiens | DNA-repair enzyme | DNA lacking 4-O-methylthymine + [protein]-S-methyl-L-cysteine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA containing 4-O-methylthymine + [protein-L-cysteine | DNA-repair enzyme | Homo sapiens | DNA lacking 4-O-methylthymine + [protein]-S-methyl-L-cysteine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AGT | - |
Homo sapiens |
O6-alkylguanine-DNA alkyltransferase | - |
Homo sapiens |