Inhibitors | Comment | Organism | Structure |
---|---|---|---|
tropolone | complete inhibition at 0.25 mM | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | the majority of COMT dopamine-methylating activity is found to be present in the cytosol | Homo sapiens | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
SK-N-MC cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dopamine + S-adenosyl-L-methionine | - |
Homo sapiens | S-adenosyl-L-homocysteine + 3-O-methyldopamine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
COMT | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | concerted action of cytosolic sulfotransferase SULT1A3 and COMT in dopamine metabolism | Homo sapiens |