Literature summary for 2.1.1.6 extracted from

Hirano, Y.; Tsunoda, M.; Shimosawa, T.; Fujita, T.; Funatsu, T.
Measurement of catechol-O-methyltransferase activity in the brain of Dahl salt-sensitive rats (2007), Biol. Pharm. Bull., 30, 2178-2180.

Search for more literature for 2.1.1.6

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	bound to	Rattus norvegicus	16020	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	Dahl salt-sensitive rats	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	membrane-bound COMT activities in the cerebral cortex are significantly reduced in high-salt loaded Dahl salt-sensitive rats compared with normal-salt loaded Dahl salt-sensitive rats	Rattus norvegicus	-
cerebellum	-	Rattus norvegicus	-
cerebral cortex	membrane-bound COMT activities in the cerebral cortex are significantly reduced in high-salt loaded Dahl salt-sensitive rats compared with normal-salt loaded Dahl salt-sensitive rats	Rattus norvegicus	-
hypophysis	-	Rattus norvegicus	-
hypothalamus	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + norepinephrine	-	Rattus norvegicus	S-adenosyl-L-homocysteine + normetanephrine	-	?

Synonyms

Synonyms	Comment	Organism
COMT	-	Rattus norvegicus

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Release 2023.1 (January 2023)