Literature summary for 2.1.1.6 extracted from

Dawling, S.; Roodi, N.; Mernaugh, R.L.; Wang, X.; Parl, F.F.
Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: comparison of wild-type and variant COMT isoforms (2001), Cancer Res., 61, 6716-6722.

Search for more literature for 2.1.1.6

Application

Application	Comment	Organism
medicine	comparison of COMT isoforms and implications for breast cancer risk	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	comparison of wild type and variant isoforms and implications for estrogen levels	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	wild type and variant isoform	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	comparison of wild type and variant isoforms and implications for estrogen levels	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)