KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.041 | - |
DNA | - |
Homo sapiens | |
0.092 | - |
DNA | - |
Homo sapiens | |
0.52 | - |
mononucleosomal DNA containing cytosine | - |
Homo sapiens | |
1.4 | - |
mononucleosomal DNA containing cytosine | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + DNA | Homo sapiens | DNMT1 interacts with hSNF2H chromatin remodeling enzyme and binds mononucleosomes with higher affinity in the presence of hSNF2H | S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P26358 | - |
- |
Homo sapiens | Q9Y6K1 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + DNA | DNMT1 interacts with hSNF2H chromatin remodeling enzyme and binds mononucleosomes with higher affinity in the presence of hSNF2H | Homo sapiens | S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine | - |
? | |
S-adenosyl-L-methionine + DNA | free DNA or assembled into a mononucleosome. The catalytic efficiency decreases on the mononucleosome 17fold | Homo sapiens | S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine | - |
? | |
S-adenosyl-L-methionine + DNA | free DNA or assembled into a mononucleosome. The catalytic efficiency decreases on the mononucleosome 8fold | Homo sapiens | S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine | - |
? | |
S-adenosyl-L-methionine + mononucleosomal DNA containing cytosine | - |
Homo sapiens | S-adenosyl-L-homocysteine + mononucleosomal DNA containing 5-methylcytosine | - |
? |