Organism | UniProt | Comment | Textmining |
---|---|---|---|
Paracentrotus lividus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | at blastula stage a proteolytic mechanism hydrolyses the enzyme present in all embryonic cells by removing a peptide of about 45000 Da from the amino terminal region of the 190000 Da enzyme initially synthesized on maternal transcripts. The resulting 145000 Da enzyme shows modified catalytic properties, different antibody reactivity and is rapidly destroyed in the few hours before gastrulation | Paracentrotus lividus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | Dnmt1 is removed from embryonic cells before gastrulation to be synthesized again at different levels in different cell types | Paracentrotus lividus | - |
additional information | Dnmt1 is removed from embryonic cells before gastrulation to be synthesized again at different levels in different cell types | Paracentrotus lividus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + DNA | - |
Paracentrotus lividus | S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Dnmt1 | - |
Paracentrotus lividus |