Literature summary for 2.1.1.2 extracted from

Heerschap, A.; Kan, H.E.; Nabuurs, C.I.; Renema, W.K.; Isbrandt, D.; Wieringa, B.
In vivo magnetic resonance spectroscopy of transgenic mice with altered expression of guanidinoacetate methyltransferase and creatine kinase isoenzymes (2007), Subcell. Biochem., 46, 119-148.

Search for more literature for 2.1.1.2

Application

Application	Comment	Organism
medicine	GAMT deficiency in mouse is associated with increased neonatal mortality, muscular hypotonia, decreased male fertility and a non-leptin-mediated life-long reduction in body weight due to reduced body fat mass	Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
S-adenosyl-L-methionine + guanidinoacetate	Mus musculus	-	S-adenosyl-L-homocysteine + creatine	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Mus musculus	-
heart	-	Mus musculus	-
liver	-	Mus musculus	-
pancreas	-	Mus musculus	-
skeletal muscle	-	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + guanidinoacetate	-	Mus musculus	S-adenosyl-L-homocysteine + creatine	-	?

Synonyms

Synonyms	Comment	Organism
GAMT	-	Mus musculus
guanidinoacetate methyltransferase	-	Mus musculus

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Release 2023.1 (January 2023)