Application | Comment | Organism |
---|---|---|
medicine | inhibition of PEMT and/or reduction of intestinal sodium concentration may be helpful in attenuating liver damage and prolonging hepatic function in intrahepatic cholestasis | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
PEMT | - |
Mus musculus |
phosphatidylethanolamine N-methyltransferase | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | lack of PEMT decreases liver damage in Abcb4-/- mice caused by exposure of the liver to excess bile acids. PEMT deficiency affects intestinal Na+ absorption resulting in an impaired Na+ concentration gradient along the length of the small intestine and abnormal absorption of bile acids mediated by apical sodium-dependent bile acid transporter | Mus musculus |