Application | Comment | Organism |
---|---|---|
medicine | medical research, expression systems allows examinations on the activation of promutagenic drugs | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
coexpressed together with a form of cytochrome P450 in Salmonella typhimurium TA1538 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ferricytochrome P450 + NADPH | Homo sapiens | involved in drug metabolism, reduced cytochrome P450 is essential for drug metabolism | 2 ferrocytochrome P450 + NADP+ + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ferricytochrome c + NADPH | - |
Homo sapiens | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
2 ferricytochrome P450 + NADPH | involved in drug metabolism, reduced cytochrome P450 is essential for drug metabolism | Homo sapiens | 2 ferrocytochrome P450 + NADP+ + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NADPH-cytochrome P450 reductase | - |
Homo sapiens |
NADPH-ferrihemoprotein reductase | - |
Homo sapiens |
NADPH:ferrihemoprotein oxidoreductase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | together with FMN | Homo sapiens | |
FMN | together with FAD | Homo sapiens | |
NADPH | - |
Homo sapiens |