KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
7.2 | - |
ethanol | microsomal ethanol oxidizing system | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Sprague-Dawley strain | - |
Rattus norvegicus Sprague-Dawley | - |
Sprague-Dawley strain | - |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.06572 | - |
purified microsomal ethanol-oxidizing system fraction | Rattus norvegicus |
0.08572 | - |
microsomes | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ferricytochrome c + NADPH | - |
Rattus norvegicus | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
2 ferricytochrome c + NADPH | - |
Rattus norvegicus Sprague-Dawley | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
additional information | as part of the microsomal ethanol-oxidizing system composed of NADPH-cytochrome c reductase, cytochrome P-450, phospholipids | Rattus norvegicus | ? | - |
? | |
additional information | aniline hydroxylase | Rattus norvegicus | ? | - |
? | |
additional information | N-demethylation of aminopyrine | Rattus norvegicus | ? | - |
? | |
additional information | N-demethylation of benzphetamine | Rattus norvegicus | ? | - |
? | |
additional information | as part of the microsomal ethanol-oxidizing system composed of NADPH-cytochrome c reductase, cytochrome P-450, phospholipids | Rattus norvegicus Sprague-Dawley | ? | - |
? | |
additional information | aniline hydroxylase | Rattus norvegicus Sprague-Dawley | ? | - |
? | |
additional information | N-demethylation of aminopyrine | Rattus norvegicus Sprague-Dawley | ? | - |
? | |
additional information | N-demethylation of benzphetamine | Rattus norvegicus Sprague-Dawley | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.9 | 7.5 | microsomal ethanol-oxidizing system | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Rattus norvegicus | |
NADPH | not replaceable by NADH | Rattus norvegicus |