Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the electron-transferring flavoprotein beta-D128N mutation occurs in a beta-turn located near the AMP binding site, a region that is involved in intersubunit contacts and establishes outer-sphere interactions with the FAD cofactor, namely at the level of the isoalloxazine moiety. Namely ETF b-D128N and ETF b-R191C,would have an impacton reactive oxygen species generation.The ETF variants show about 70% decreased activity in comparison with the wild-type protein, and establish a rationale for their functional defects | Homo sapiens | ? | - |
? | |
reduced electron-transferring flavoprotein + ubiquinone | electron transfer via flavin cofactor | Homo sapiens | electron-transferring flavoprotein + ubiquinol | - |
r |