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Literature summary for 1.5.1.33 extracted from

  • Kazemi, B.; Tohidi, F.; Bandehpour, M.; Yarian, F.
    Molecular cloning, expression and enzymatic assay of pteridine reductase 1 from Iranian lizard Leishmania (2010), Iran. Biomed. J., 14, 97-102.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli strain JM109 Leishmania sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
51000
-
x * 51000, SDS-PAGE Leishmania sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-biopterin + NADPH + H+ Leishmania sp.
-
5,6,7,8-tetrahydrobiopterin + NADP+
-
?
6-biopterin + NADPH + H+ Leishmania sp. BK-2007
-
5,6,7,8-tetrahydrobiopterin + NADP+
-
?

Organism

Organism UniProt Comment Textmining
Leishmania sp. A2TEY0
-
-
Leishmania sp. BK-2007 A2TEY0
-
-

Purification (Commentary)

Purification (Comment) Organism
T7 Tag antibody agarose column chromatography Leishmania sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-biopterin + NADPH + H+
-
Leishmania sp. 5,6,7,8-tetrahydrobiopterin + NADP+
-
?
6-biopterin + NADPH + H+
-
Leishmania sp. BK-2007 5,6,7,8-tetrahydrobiopterin + NADP+
-
?

Subunits

Subunits Comment Organism
? x * 51000, SDS-PAGE Leishmania sp.

Synonyms

Synonyms Comment Organism
pteridine reductase 1
-
Leishmania sp.
PTR1
-
Leishmania sp.

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Leishmania sp.