Application | Comment | Organism |
---|---|---|
medicine | significantly reduced inflammatory responses and mortality are observed in zebrafish infected with Staphylococcus aureus pre-incubated with grape seed extract. Grape seed extract might serve as an effective natural alternative for the control of food poisoning caused by Staphylococcus aureus with proper safety measure | Staphylococcus aureus |
Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli as a His-tagged fusion protein | Staphylococcus aureus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
grape seed extract | grape seed extract inhibits the dihydrofolate reductase activity and growth of Staphylococcus aureus. The grape seed extract-induced growth inhibition is reversed by adding, tetrahydrofolate, 5,10-methylenetetrahydrofolate or methionine to the medium | Staphylococcus aureus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dihydrofolate + NADPH + H+ | - |
Staphylococcus aureus | tetrahydrofolate + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DHFR | - |
Staphylococcus aureus |
dihydrofolate reductase | - |
Staphylococcus aureus |