Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.5.1.3 extracted from

  • Fernandes, N.; Figueiredo, P.; do Rosario, V.E.; Cravo, P.
    Analysis of sulphadoxine/pyrimethamine resistance-conferring mutations of Plasmodium falciparum from Mozambique reveals the absence of the dihydrofolate reductase 164L mutant (2007), Malar. J., 6, 35.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine in a total of 92 Plasmodium falsiparum-infected blood samples from children in Mozambique, the frequency of the sulphadoxine/pyrimethamine resistance-associated dihydrofolate reductase triple mutants 51I/59R/108N and of dihydrofolate reductase /dihydropteroate synthetase quintuple mutants 51I/59R/108N + 437G/540E was 93% and 47%, respectively. However, no dihydrolfolate reductase 164L mutants were detected Plasmodium falciparum

Organism

Organism UniProt Comment Textmining
Plasmodium falciparum
-
isolates from Mozambique
-