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Literature summary for 1.4.3.4 extracted from

  • Senatori, O.; Setini, A.; Scirocco, A.; Nicotra, A.
    Effect of short-time exposures to nickel and lead on brain monoamine oxidase from Danio rerio and Poecilia reticulata (2009), Environ. Toxicol., 24, 309-313.
    View publication on PubMed
Search for more literature for 1.4.3.4

Inhibitors

Inhibitors Comment Organism Structure
Clorgyline complete inhibition at 0.01 mM Danio rerio
Clorgyline complete inhibition at 0.01 mM Poecilia reticulata
Deprenyl complete inhibition at 0.01 mM Danio rerio
Deprenyl complete inhibition at 0.01 mM Poecilia reticulata

Organism

Organism UniProt Comment Textmining
Danio rerio Q6NSN2
-
-
Poecilia reticulata Q0PGS2
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Danio rerio
-
brain
-
 Poecilia reticulata
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.162
-
 brain enzyme Poecilia reticulata
0.243
-
 brain enzyme Danio rerio

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tyramine + H2O + O2
-
 Danio rerio (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
 ?
tyramine + H2O + O2
-
 Poecilia reticulata (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
MAO
-
 Danio rerio
MAO
-
 Poecilia reticulata

Expression

Organism Comment Expression
Danio rerio Ni2+ and Pb2+ reduce the expression of MAO in brain after exposure over 24 h and 72 h, overview down
Poecilia reticulata Ni2+ and Pb2+ induce the expression of MAO in brain after exposure over 24 h, but the expression level is normalized after 72 h, overview up