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Literature summary for 1.4.3.4 extracted from

  • Inagaki, T.; Rao, N.A.; Yagi, K.
    Modulation by phospholipids of the activity of monoamine oxidase purified from pig liver (1986), J. Biochem., 100, 597-603.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Clorgyline MAO-A highly sensitive and MAO-B less sensitive to inhibition Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information effect of phospholipids on Km Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Sus scrofa 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
58000
-
x * 58000, SDS-PAGE Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
additional information lipid environment is essential for enzymatic activity, lipid microenvironment may regulate the mode of action of the enzyme in the mitochondrial outer membrane Sus scrofa

Purification (Commentary)

Purification (Comment) Organism
-
Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Sus scrofa
-
spleen
-
Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phenylethylamine + H2O + O2
-
Sus scrofa 2-phenylethanal + NH3 + H2O2
-
?
benzylamine + H2O + O2
-
Sus scrofa benzaldehyde + NH3 + H2O2
-
?
RCH2NH2 + H2O + O2
-
Sus scrofa RCHO + NH3 + H2O2
-
?
serotonin + H2O + O2
-
Sus scrofa (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
?

Subunits

Subunits Comment Organism
? x * 58000, SDS-PAGE Sus scrofa

Synonyms

Synonyms Comment Organism
More isoforms differ in inhibitor sensitivity Sus scrofa
More MAO-A and MAO-B are 2 different isoenzymic forms which differ in substrate specificity, distribution among tissues and their structures Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8 9 purified enzyme Sus scrofa