Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,2'-dipyridyl disulfide | - |
Homo sapiens | |
amphetamine | a competitive inhibitor of MAO-A | Homo sapiens | |
Clorgyline | - |
Homo sapiens | |
Deprenyl | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Km of membrane-bound and Triton X-100-solubilized enzyme | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
RCH2NH2 + H2O + O2 | Homo sapiens | important functions in the metabolism of biogenic amines in the central nervous system and peripheral tissues | RCHO + NH3 + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
kynuramine + H2O + O2 | - |
Homo sapiens | 3-(2-aminophenyl)-3-oxopropanal + NH3 + H2O2 | - |
? | |
RCH2NH2 + H2O + O2 | - |
Homo sapiens | RCHO + NH3 + H2O2 | - |
? | |
RCH2NH2 + H2O + O2 | important functions in the metabolism of biogenic amines in the central nervous system and peripheral tissues | Homo sapiens | RCHO + NH3 + H2O2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 60000-64000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
More | isoforms differ in inhibitor sensitivity | Homo sapiens |
More | MAO-A and MAO-B are 2 different isoenzymic forms which differ in substrate specificity, distribution among tissues and their structures | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2.08 | - |
kynuramine | MAO-A | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
flavin | flavoprotein | Homo sapiens | |
flavin | 1 flavin per subunit | Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.02 | - |
amphetamine | - |
Homo sapiens |