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Literature summary for 1.4.3.4 extracted from

  • Pearce, L.B.; Roth, J.A.
    Human brain monoamine oxidase: solubilization and kinetics of inhibition by octylglucoside (1983), Arch. Biochem. Biophys., 224, 464-472.
    View publication on PubMed
Search for more literature for 1.4.3.4

Inhibitors

Inhibitors Comment Organism Structure
1-O-n-octyl-beta-D-glucopyranoside at concentrations well below the critical micelle concentration Homo sapiens
Clorgyline irreversible inhibitor Homo sapiens
Deprenyl
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information Km of membrane-bound and 1-O-n-octyl-beta-D-glucopyranoside-treated enzyme Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Organic Solvent Stability

Organic Solvent Comment Organism
additional information 1-O-n-octyl-beta-D-glucopyranoside, solubilizes enzyme without dramatically altering the lipid microenviroment, a state analogous to the native species Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phenylethylamine + H2O + O2 MAO-B selective substrate Homo sapiens 2-phenylethanal + NH3 + H2O2
-
 ?
dopamine + H2O + O2
-
 Homo sapiens (3,4-dihydroxyphenyl)acetaldehyde + NH3 + H2O2
-
 ?
RCH2NH2 + H2O + O2 5-hydroxytryptamine, MAO-A selective substrate Homo sapiens RCHO + NH3 + H2O2
-
 ?
tyramine + H2O + O2 nonselective substrate Homo sapiens (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
 ?