Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ADP | ADP activation is almost abolished after treatment with TLCK-treated chymotrypsin | Bos taurus | |
chymotrypsin | 0.2 mg/ml chymotrypsin cleaves glutamate dehydrogenase in such a fashion as to cause a rise in activity with NADP+ and NAD+ as coenzyme, over threefold activation in the NADP+ assay with TLCK-treated chymotrypsin, the distinguishing aspect with untreated chymotrypsin is that the activation is followed by a decrease in activity | Bos taurus | |
additional information | not inhibited by trypsin | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
GTP | GTP inhibition is attenuated to some extent by the proteolysis with TLCK-treated chymotrypsin | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate + H2O + NAD(P)+ | - |
Bos taurus | 2-oxoglutarate + NH3 + NAD(P)H + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GDH | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Bos taurus | |
NADP+ | - |
Bos taurus |