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Literature summary for 1.4.1.2 extracted from

  • Girinathan, B.P.; Braun, S.E.; Govind, R.
    Clostridium difficile glutamate dehydrogenase is a secreted enzyme that confers resistance to H2O2 (2014), Microbiology, 160, 47-55.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.4.1.2

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
 Clostridioides difficile
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48000
-
 3 * 48000, SDS-PAGE Clostridioides difficile
150000
-
 PAGE Clostridioides difficile

Organism

Organism UniProt Comment Textmining
Clostridioides difficile
-
-
-
Clostridioides difficile JIR8094
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
culture fluid
-
 Clostridioides difficile
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamate + NAD+ + H2O
-
 Clostridioides difficile 2-oxoglutarate + NADH + NH3
-
 ir
L-glutamate + NAD+ + H2O
-
 Clostridioides difficile JIR8094 2-oxoglutarate + NADH + NH3
-
 ir

Subunits

Subunits Comment Organism
trimer 3 * 48000, SDS-PAGE Clostridioides difficile

General Information

General Information Comment Organism
physiological function a gene disruption mutant fails to produce and secrete glutamate dehydrogenase. In tryptose yeast extract medium, the gluD mutant grows slower than the parent strain. The mutant displys higher sensitivity to H2O2 Clostridioides difficile