Application | Comment | Organism |
---|---|---|
biotechnology | a strategy to control flocculation is investigated using dimorphic yeast, Benjaminiella poitrasii as a model. Parent form of this yeast (Y) exhibit faster flocculation (11.1 min) than the monomorphic yeast form mutant Y-5 (12.6 min). Flocculation of both Y and Y-5 can be altered by supplementing either substrates or inhibitor of NAD-glutamate dehydrogenase (NAD-GDH) in the growth media. The rate of flocculation is promoted by alpha-ketoglutarate or isophthalic acid and decelerated by glutamate with a statistically significant inverse correlation to corresponding NAD-GDH levels. This opens up new possibilities of using NAD-GDH modulating agents to control flocculation in fermentations for easier downstream processing | Benjaminiella poitrasii |
biotechnology | the rate of flocculation is promoted by a-ketoglutarate or isophthalic acid and decelerated by glutamate with a statistically significant inverse correlation to corresponding NAD-GDH levels. These interesting findings open up new possibilities of using NAD-GDH modulating agents to control flocculation in fermentations for easier downstream processing | Benjaminiella poitrasii |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
isophthalic acid | - |
Benjaminiella poitrasii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Benjaminiella poitrasii | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxoglutarate + NADH + NH3 | - |
Benjaminiella poitrasii | L-glutamate + NAD+ + H2O | - |
? | |
L-glutamate + H2O + NADP+ | - |
Benjaminiella poitrasii | 2-oxoglutarate + NH3 + NADPH | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NAD-GDH | - |
Benjaminiella poitrasii |
NAD-glutamate dehydrogenase | - |
Benjaminiella poitrasii |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Benjaminiella poitrasii |