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Literature summary for 1.3.1.9 extracted from

  • Mehboob, S.; Truong, K.; Santarsiero, B.D.; Johnson, M.E.
    Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD(+) and triclosan (2010), Acta Crystallogr. Sect. F, 66, 1436-1440.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.3.1.9

Cloned(Commentary)

Cloned (Comment) Organism
-
 Francisella tularensis

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with NAD+ and triclosan, to 2.1 A resolution. The substrate-binding loop, residues 191–205, undergoes a major conformational change upon binding to triclosan and forms a lid on top of the triclosan moiety and the nicotinamide group that shields them from the solvent Francisella tularensis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
29968
-
 x * 29968, calculated Francisella tularensis

Organism

Organism UniProt Comment Textmining
Francisella tularensis Q5NGQ3
-
-
Francisella tularensis SCHU S4 Q5NGQ3
-
-

Subunits

Subunits Comment Organism
? x * 29968, calculated Francisella tularensis
More exists in different oligomeric forms that are dependent on concentration. At concentrations from 60 to 138 mM, enzyme exists as a tetramer, while at concentrations below 8 mM a dimeric unit is seen, according to dynamic light-scattering studies and size-exclusion studies Francisella tularensis

Synonyms

Synonyms Comment Organism
FabI
-
 Francisella tularensis
FTT_0782 locus name Francisella tularensis