Application | Comment | Organism |
---|---|---|
medicine | antibacterial target | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(2,4-dichlorophenoxy)-5-chlorophenol | triclosan, dissociation constant of the inhibitor from the enzyme-NAD+ product complex: 7.0 pM | Escherichia coli | |
2-phenoxyphenol | PP, dissociation constant of the inhibitor from the enzyme-NAD+ product complex: 0.5 microM | Escherichia coli | |
5-chloro-2-phenoxyphenol | CPP, dissociation constant of the inhibitor from the enzyme-NAD+ product complex: 1.1 pM | Escherichia coli | |
5-fluoro-2-phenoxyphenol | FPP, dissociation constant of the inhibitor from the enzyme-NAD+ product complex: 1.5 nM | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-[acyl-carrier protein] + NAD+ | Escherichia coli | - |
trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P0AEK4 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-[acyl-carrier protein] + NAD+ | - |
Escherichia coli | trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
enoyl reductase | - |
Escherichia coli |
enoyl-[acyl-carrier-protein] reductase | - |
Escherichia coli |
FabI | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Escherichia coli |