Application | Comment | Organism |
---|---|---|
medicine | antibacterial target | Toxoplasma gondii |
Cloned (Comment) | Organism |
---|---|
into the pMALc2x vector without signal peptide coding sequence, a second construct contains in addition the sequence of the TEV protease cleaving site followed by a hexahistidine tag | Toxoplasma gondii |
Crystallization (Comment) | Organism |
---|---|
crystals of enoyl reductase in complex with NAD+ and triclosan, data are collected to beyond 2.6 A | Toxoplasma gondii |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
triclosan | - |
Toxoplasma gondii |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-[acyl-carrier protein] + NAD+ | Toxoplasma gondii | - |
trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Toxoplasma gondii | - |
- |
- |
Purification (Comment) | Organism |
---|---|
using a HiTrap Chelating HP and an amylose column | Toxoplasma gondii |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-[acyl-carrier protein] + NAD+ | - |
Toxoplasma gondii | trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
enoyl reductase | - |
Toxoplasma gondii |
enoyl-[acyl-carrier-protein] reductase | - |
Toxoplasma gondii |
ENR | - |
Toxoplasma gondii |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Toxoplasma gondii |